There are over 40 known virus and 60 diseases directly associated with birds and their droppings. These diseases vary in seriousness from minor stomach ailments to fatal diseases such as histoplasmosis, which is the one disease which is now most common.
Histoplasmosis is a fungus which is found in the soil, particularly soil with high nitrogen content and it is enriched by the droppings of birds and bats. It thrives in warm temperatures and in moist conditions especially in areas such as bird roosts, caves infested with bats, school yards, chicken coops, areas where there is rotten or decaying wood etc. It is contracted when the soil from an infected area is disturbed and tiny spores are inhaled. These spores enter the lungs and can then be transported around the body.
Birds can carry histoplasmosis fungus on their legs, feet, wings etc. but they are not infected with histoplasmosis, most likely because of their high body temperature. However bats do carry and do excrete histoplasmosis. Apart from humans, animals such as dogs, cats, rats, skunks, foxes etc. also are susceptible to this disease.
Dust and dirt containing histoplasmosis spores can be carried over a long distance and hence can affect a number of workers on an infected site.
Several cases of Cryptococcocal meningitis have been reported where workers exposed to bird droppings have developed a chronic inflammation of the brain tissue. A window cleaner in California lost 50% of his lung capacity because he came into regular contact with bird droppings on window ledges.
Water sprays and other dust suppression methods should be used when handling dirt/droppings in infected areas.
The only known product to kill these spores is a 3% solution of formaldehyde however workers in potentially infected areas should take necessary precautions. Wear a respirator with a hepa filter and certainly wet droppings down before clean up and removal.